How we scored it
Amide of palmitic acid and a tetrapeptide of natural amino acids, same pattern as Palmitoyl Pentapeptide-4. 100% natural.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Made by coupling palmitic acid to a synthetic tetrapeptide assembled from natural amino acids. Coupling reagents leave no mass in the final molecule.
In plain English
A skin-conditioning peptide ingredient made from a fatty acid attached to a chain of four amino acids. Used in anti-ageing skincare formulas.
CosIng definition: Palmitoyl Tetrapeptide-10 is the product obtained by the reaction of palmitic acid and Tetrapeptide-10
Structure
(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Tetrapeptide-10. PubChem CID 24967468. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL TETRAPEPTIDE-10. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL TETRAPEPTIDE-10. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20TETRAPEPTIDE-10