Database/Hair Conditioning/Palmitoyl Proline
100% natural origin · ISO 16128

Is Palmitoyl Proline natural?

Yes. Palmitic acid, an oleochemical fatty acid, amide-linked to proline, a fermentation-derived amino acid; both fragments are natural origin.

INCI namePalmitoyl Proline
CAS59441-32-6
FormulaC21H39NO3 · 353.5 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockMade by acylating proline (a fermentation-derived amino acid)…

How we scored it

Hexadecanoyl (palmitic acid, C16H31O) amide-bonded to proline (amino acid) minus condensation water; both fragments natural: oleochemical fatty acid + fermentation amino acid. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acylating proline (a fermentation-derived amino acid) with palmitic acid from vegetable oil. No petrochemical fragment remains in the final molecule.

In plain English

A compound combining palmitic acid, a fatty acid from plant oil, with proline, an amino acid. Used to condition skin and hair, built from natural fat and amino-acid sources.

Structure

2D structure of Palmitoyl Proline

(2S)-1-hexadecanoylpyrrolidine-2-carboxylic acid

PubChem CID 15384561 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Palmitoyl Proline. PubChem CID 15384561. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PALMITOYL PROLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PALMITOYL PROLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20PROLINE