Database/Skin Conditioning/Palmitoyl Octapeptide-24
100% natural origin · ISO 16128

Is Palmitoyl Octapeptide-24 natural?

Yes. Palmitic acid comes from palm or coconut oil and the peptide is built from fermentation-derived amino acids; the chloride reagent leaves no mass.

INCI namePalmitoyl Octapeptide-24
FunctionSkin Conditioning
FeedstockDominant route couples palmitoyl chloride, made from palm…

How we scored it

Palmitoyl C16H31O 239.4 natural (palm oil); chloride leaves; octapeptide from amino acids natural (sequence assumed proteinogenic); 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route couples palmitoyl chloride, made from palm oil palmitic acid, to a peptide assembled from fermentation-derived amino acids. Protecting groups and coupling agents leave no mass.

In plain English

A peptide with a fatty-acid tail used as a skin-conditioning ingredient in creams. The palmitic acid tail comes from palm or coconut oil and the amino acids from fermentation or protein hydrolysis.

CosIng definition: Palmitoyl Octapeptide-24 is the product obtained by the reaction of palmitoyl chloride and Octapeptide-25

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2PALMITOYL OCTAPEPTIDE-24. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3PALMITOYL OCTAPEPTIDE-24. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20OCTAPEPTIDE-24