Database/Skin Protecting/Palmitoyl Isoleucine
100% natural origin · ISO 16128

Is Palmitoyl Isoleucine natural?

Yes. Palmitic acid, an oleochemical fatty acid, amide-linked to isoleucine, a fermentation-derived amino acid; both fragments are natural origin.

INCI namePalmitoyl Isoleucine
CAS54617-29-7
FormulaC22H43NO3 · 369.6 Da
FunctionSkin Protecting
FeedstockMade by acylating isoleucine (a fermentation-derived amino acid)…

How we scored it

Hexadecanoyl (palmitic acid) amide-bonded to isoleucine (amino acid) minus condensation water; both fragments natural: oleochemical fatty acid + fermentation amino acid. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acylating isoleucine (a fermentation-derived amino acid) with palmitic acid from vegetable oil. No petrochemical fragment remains in the molecule.

In plain English

A compound combining palmitic acid, a plant-oil fatty acid, with isoleucine, an amino acid. Used to protect and condition skin, built from natural fat and amino-acid sources.

CosIng definition: L-Isoleucine, N-(1-oxohexadecyl)-

Structure

2D structure of Palmitoyl Isoleucine

(2S,3S)-2-(hexadecanoylamino)-3-methylpentanoic acid

PubChem CID 14993927 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Palmitoyl Isoleucine. PubChem CID 14993927. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PALMITOYL ISOLEUCINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PALMITOYL ISOLEUCINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20ISOLEUCINE