Database/Skin Conditioning/Palmitoyl Glutamic Acid
100% natural origin · ISO 16128

Is Palmitoyl Glutamic Acid natural?

Yes. Amide of oleochemical palmitic acid and fermentation-derived glutamic acid; both building blocks natural.

INCI namePalmitoyl Glutamic Acid
CAS38079-66-2
FormulaC21H39NO5 · 385.5 Da
FunctionSkin Conditioning
FeedstockMade by amide-coupling palm/coconut-derived palmitic acid with L-glutamic…

How we scored it

Palmitic acid (256.4, oleochemical) + glutamic acid (147.1, fermentation) − H2O (18, condensation) = 385.5, matches MW; both fragments natural → 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by amide-coupling palm/coconut-derived palmitic acid with L-glutamic acid from fermentation. Assumes oleochemical fatty-acid supply typical for cosmetic grade.

In plain English

A conditioning ingredient made from palm-oil fatty acid joined to the amino acid glutamic acid. Used in skincare to help condition skin. Built from plant oil and a fermentation-derived amino acid.

Structure

2D structure of Palmitoyl Glutamic Acid

(2S)-2-(hexadecanoylamino)pentanedioic acid

PubChem CID 161955 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Palmitoyl Glutamic Acid. PubChem CID 161955. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PALMITOYL GLUTAMIC ACID. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PALMITOYL GLUTAMIC ACID. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20GLUTAMIC%20ACID