Database/Skin Conditioning/Palmitoyl Dipeptide-7
100% natural origin · ISO 16128

Is Palmitoyl Dipeptide-7 natural?

Yes. Palmitic acid is from palm or coconut oil, and lysine and threonine come from fermentation, so every atom is natural origin.

INCI namePalmitoyl Dipeptide-7
CAS911813-90-6
FormulaC26H51N3O5 · 485.7 Da
FunctionSkin Conditioning
FeedstockDominant route couples fermentation-derived lysine and threonine by…

How we scored it

Palmitoyl C16H31O 239 + Lys-Thr residue 246 = 485 Da (C26H51N3O5); all fragments natural, so 485/485 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route couples fermentation-derived lysine and threonine by peptide synthesis and acylates with palmitic acid from palm or coconut oil. Protecting groups and coupling agents leave no mass in the product.

In plain English

A fatty-acid-linked peptide: palmitic acid joined to two amino acids, lysine and threonine. It is used as a skin-conditioning ingredient. The fatty acid comes from palm or coconut oil and the amino acids from fermentation.

CosIng definition: Palmitoyl Dipeptide-7 is the reaction product of palmitic acid and Dipeptide-7

Structure

2D structure of Palmitoyl Dipeptide-7

(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoic acid

PubChem CID 11962376 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Palmitoyl Dipeptide-7. PubChem CID 11962376. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PALMITOYL DIPEPTIDE-7. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PALMITOYL DIPEPTIDE-7. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20DIPEPTIDE-7