How we scored it
Palmitic acid + Dipeptide-5 + diaminobutyroyl + hydroxythreonine (all natural amino-acid-family units) joined by amide bonds. Whole molecule = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Made by chemically coupling palm/coconut-derived palmitic acid to a small peptide built from fermentation-derived and modified amino acids. Synthesis reagents and protecting groups leave no mass in the product.
In plain English
A skin-conditioning peptide active made by attaching palm or coconut-derived palmitic acid to a small chain of amino acids. It is manufactured by chemically joining these natural building blocks together.
CosIng definition: Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is the product of the reaction of palmitic acid and diaminobutyroyl hydroxythreonine with Dipeptide-5
Structure
(2S,3R)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]butanoyl]amino]-3-hydroxybutanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine. PubChem CID 72941935. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20DIPEPTIDE-5%20DIAMINOBUTYROYL%20HYDROXYTHREONINE