How we scored it
Palmitoyl C16H31O 239.4 (palm oil) + Ala residue 71.1 + His residue 137.1 (fermentation) + OH 17.0; amide-linked, no petrochemical cap: 464.6/464.6 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Palmitic acid from palm or coconut oil is coupled to an alanine-histidine dipeptide made from fermentation-derived amino acids. No petrochemical cap or reagent leaves mass in the product.
In plain English
A small lipid-linked peptide: palmitic acid joined to the dipeptide alanine-histidine. The fatty tail helps it stay in the skin, and it is used as a skin-conditioning ingredient. Palmitic acid comes from palm oil and the amino acids from fermentation.
CosIng definition: Palmitoyl Dipeptide-10 is the product of the reaction of palmitic acid and Dipeptide-10
Structure
(2S)-2-[[(2S)-2-(hexadecanoylamino)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Dipeptide-10. PubChem CID 117847167. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL DIPEPTIDE-10. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL DIPEPTIDE-10. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20DIPEPTIDE-10