How we scored it
Palmitoyl C16H31O from palm or coconut oil is natural, plus a decapeptide of amino acids (natural); protecting groups and coupling agents leave no mass: 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route: peptide synthesis from fermentation-derived amino acids, then N-acylation with palm or coconut-derived palmitic acid. No alternative route is commercially significant.
In plain English
A chain of ten amino acids joined to palmitic acid, a fatty acid from palm or coconut oil, used to condition skin. The amino acids come from fermentation or protein hydrolysis and are linked by chemical synthesis.
CosIng definition: Palmitoyl Decapeptide-21 is the product obtained by the reaction of palmitic acid and Decapeptide-21.
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2PALMITOYL DECAPEPTIDE-21. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3PALMITOYL DECAPEPTIDE-21. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20DECAPEPTIDE-21