Database/Hair Conditioning/Palmitoyl Arginine
100% natural origin · ISO 16128

Is Palmitoyl Arginine natural?

Yes. Amide of oleochemical palmitic acid and fermentation-derived arginine; both building blocks natural, coupling loses only water.

INCI namePalmitoyl Arginine
CAS58725-47-6
FormulaC22H44N4O3 · 412.6 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockMade by amide-coupling palm/coconut-derived palmitic acid with L-arginine…

How we scored it

Palmitic acid (256.4, oleochemical) + arginine (174.2, fermentation) − H2O (18, condensation, no mass loss to petro) = 412.6, matches MW; both fragments natural → 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by amide-coupling palm/coconut-derived palmitic acid with L-arginine from microbial fermentation. Assumes oleochemical fatty-acid supply typical for cosmetic grade; a minor synthetic-fatty-acid route exists industrially.

In plain English

A conditioning ingredient made by joining palm-oil fatty acid to the amino acid arginine. Used in hair and skin products to help condition. Built from plant oil and a fermentation-derived amino acid.

Structure

2D structure of Palmitoyl Arginine

(2S)-5-(diaminomethylideneamino)-2-(hexadecanoylamino)pentanoic acid

PubChem CID 11223678 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Palmitoyl Arginine. PubChem CID 11223678. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PALMITOYL ARGININE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PALMITOYL ARGININE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20ARGININE