Database/Skin Conditioning/Osthole
100% natural origin · ISO 16128

Is Osthole natural?

Yes. Entire molecule is a plant-derived coumarin extracted from Cnidium or Angelica root material; no synthetic fragment.

INCI nameOsthole
CAS484-12-8
FormulaC15H16O3 · 244.28 Da
FunctionSkin Conditioning
FeedstockCommercially obtained by extraction and isolation from Cnidium…

How we scored it

Single coumarin molecule, commercially isolated intact from plant material; no fragments to split.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Commercially obtained by extraction and isolation from Cnidium monnieri fruit or Angelica root, its natural source. Chemical synthesis is possible but is not the typical cosmetic-grade supply route.

In plain English

A natural compound isolated from plants such as Cnidium and Angelica, used in skincare for its skin-conditioning properties.

Structure

2D structure of Osthole

7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one

PubChem CID 10228 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Osthole. PubChem CID 10228. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OSTHOLE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OSTHOLE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OSTHOLE