Database/Bleaching/Oligopeptide-68
100% natural origin · ISO 16128

Is Oligopeptide-68 natural?

Yes. A plain synthetic peptide of natural amino acids with no synthetic fatty or acetyl cap indicated.

INCI nameOligopeptide-68
CAS1206525-47-4
FormulaC62H91N17O21 · 1410.5 Da
FunctionBleaching
FeedstockAssembled from fermentation-derived amino acids via peptide synthesis.…

How we scored it

12-residue peptide (Arg, Asp, Gly, Gln, Ile, Leu, Ser, Thr, Trp, Tyr) with no cap described; amide-linked amino acids are natural. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Assembled from fermentation-derived amino acids via peptide synthesis. No extraction route exists at commercial scale.

In plain English

A synthetic peptide built from 12 amino acids, used as a skin-brightening ingredient. Its building blocks trace back to fermentation, though it's assembled in a lab.

CosIng definition: Oligopeptide-68 is the synthetic peptide containing 12 amino acids consisting of arginine, aspartic acid, glycine, glutamine, isoleucine, leucine, serine, threonine, tryptophan and tyrosine

Structure

2D structure of Oligopeptide-68

(2S)-5-amino-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoic acid

PubChem CID 163285842 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Oligopeptide-68. PubChem CID 163285842. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OLIGOPEPTIDE-68. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OLIGOPEPTIDE-68. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-68