Database/Skin Conditioning/Oligopeptide-55
100% natural origin · ISO 16128

Is Oligopeptide-55 natural?

Yes. Every residue is a proteinogenic amino acid from fermentation or protein hydrolysis, and the INCI name shows no petrochemical acyl cap.

INCI nameOligopeptide-55
FunctionSkin Conditioning
FeedstockDominant route: solid-phase or solution peptide synthesis from…

How we scored it

12-residue peptide of proteinogenic amino acids (Asn, Asp, Ile, Leu, Met, Phe, Ser, Thr); no acetyl or lipid cap is named; peptides = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route: solid-phase or solution peptide synthesis from fermentation-derived L-amino acids; protecting groups and coupling agents leave no mass. No alternative route is commercially significant.

In plain English

A short peptide, a chain of twelve amino acids, used to condition skin. It is built from natural amino acids (asparagine, aspartic acid, isoleucine, leucine, methionine, phenylalanine, serine and threonine) that are made by fermentation or protein hydrolysis.

CosIng definition: Oligopeptide-55 is a synthetic peptide composed of 12 amino acids consisting of asparagine, aspartic acid, isoleucine, leucine, methionine, phenylalanine, serine, and threonine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-55. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-55. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-55