How we scored it
12-residue peptide of 9 amino acids (Arg, Asp, Gln, Gly, Ile, Leu, Ser, Thr, Trp); no caps named. Reagents and protecting groups leave no mass. 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route is solid-phase synthesis from fermentation-derived L-amino acids, the standard method for short cosmetic peptides. A recombinant or enzymatic route would give the same atom accounting.
In plain English
A short synthetic chain of 12 amino acids. It is listed as a skin-conditioning ingredient. It is built in a lab by joining amino acids, which come from fermentation or plant protein, in a set order.
CosIng definition: Oligopeptide-50 is a synthetic peptide containing 12 amino acids consisting of arginine, aspartic acid, glutamine, glycine, isoleucine, leucine, serine, threonine, and tryptophan
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2OLIGOPEPTIDE-50. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3OLIGOPEPTIDE-50. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-50