How we scored it
35-residue peptide built from 11 amino acids (Ala, Arg, Asn, Asp, Gln, Glu, Gly, Ile, Lys, Thr, Pro); no caps named. Reagents and protecting groups leave no mass. 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route is stepwise peptide synthesis (solid-phase or recombinant expression) from fermentation-derived L-amino acids. Either route gives the same atom accounting.
In plain English
A longer synthetic chain of 35 amino acids. It is listed as a skin-conditioning ingredient. It is built in a lab by joining amino acids, which come from fermentation or plant protein, in a set order.
CosIng definition: Oligopeptide-49 is a synthetic 35 amino acid peptide consisting of alanine, arginine, asparagine, aspartic acid, glutamine, glutamic acid, glycine, isoleucine, lysine, threonine, and proline
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2OLIGOPEPTIDE-49. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3OLIGOPEPTIDE-49. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-49