Database/Skin Conditioning/Oligopeptide-44
100% natural origin · ISO 16128

Is Oligopeptide-44 natural?

Yes. All residues are amino acids from fermentation or protein hydrolysate; synthesis reagents and protecting groups leave no mass in the final peptide.

INCI nameOligopeptide-44
FunctionSkin Conditioning
FeedstockFermentation-derived amino acids are coupled by solid-phase peptide…

How we scored it

11-residue peptide of Asp, Cys, Gln, Gly, His, Phe, Ser, Thr, Tyr; no cap listed in CosIng; all residues natural amino acids (cysteine S is amino-acid sulfur); full mass natural, 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Fermentation-derived amino acids are coupled by solid-phase peptide synthesis into the 11-residue chain. No alternative route is significant.

In plain English

A synthetic chain of eleven amino acids used to condition skin. It is assembled in a lab from amino acids that are normally produced by fermentation or protein hydrolysis.

CosIng definition: Oligopeptide-44 is a synthetic 11 amino acid peptide consisting of aspartic acid, cysteine, glutamine, glycine, histidine, phenylalanine, serine, threonine, and tyrosine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-44. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-44. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-44