Database/Skin Conditioning/Oligopeptide-34
100% natural origin · ISO 16128

Is Oligopeptide-34 natural?

Yes. A palmitoyl-capped peptide; the C16 fatty cap and amino acids are both oleochemical/fermentation natural origin, unlike a petrochemical acetyl cap.

INCI nameOligopeptide-34
FormulaC38H68N6O8 · 737.0 Da
FunctionSkin Conditioning
FeedstockMade by attaching a palmitic-acid (coconut/palm oleochemical) fatty…

How we scored it

Peptide N-capped with hexadecanoyl (palmitoyl, C16 fatty acid) per the IUPAC fragment; amino acids and the palmitic-acid cap are both natural. 737/737 = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by attaching a palmitic-acid (coconut/palm oleochemical) fatty chain to a synthetic amino-acid peptide. No petrochemical fatty-cap route is used.

In plain English

A small peptide fitted with a natural palm-oil-derived fatty tail to help it absorb into skin. Both the amino acids and the fatty tail come from natural sources.

CosIng definition: Oligopeptide-34 is a synthetic peptide containing 13 amino acids consisting of arginine, aspartic acid, isoleucine, glutamine, leucine, serine, threonine, and tryptophan

Structure

2D structure of Oligopeptide-34

2-[[1-[2-[[2-[[2-[[2-(hexadecanoylamino)-3-methylbutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid

PubChem CID 71435492 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Oligopeptide-34. PubChem CID 71435492. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OLIGOPEPTIDE-34. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OLIGOPEPTIDE-34. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-34