How we scored it
12 amino-acid residues (Ala, Arg, His, Ile, Leu, Lys, Pro, Ser), all n = 1; no acyl cap in the INCI name; coupling reagents and protecting groups leave no mass. 100% = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Dominant route is chemical peptide synthesis from fermentation- or hydrolysate-derived amino acids. Recombinant or enzymatic production, where used, also yields only amino-acid mass, so the value is unchanged.
In plain English
A synthetic 12-amino-acid peptide listed in cosmetics for antioxidant, binding, chelating and skin-protecting roles. It is built in a laboratory by joining amino acids, which come from fermentation or from hydrolysed plant and animal protein.
CosIng definition: Oligopeptide-28 is a synthetic peptide containing 12 amino acids consisting of alanine, arginine, histidine, isoleucine, leucine, lysine, proline, and serine
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2OLIGOPEPTIDE-28. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3OLIGOPEPTIDE-28. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-28