Database/Skin Conditioning/Oligopeptide-27
100% natural origin · ISO 16128

Is Oligopeptide-27 natural?

Yes. Every residue is an amino acid from fermentation or protein hydrolysate, and the synthesis reagents leave no mass in the final peptide.

INCI nameOligopeptide-27
FunctionSkin Conditioning
FeedstockDominant route is chemical peptide synthesis from fermentation-…

How we scored it

40 amino-acid residues, all n = 1 (fermentation or hydrolysate); no acyl cap in the INCI name; coupling reagents and protecting groups leave no mass. Natural mass 100% = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route is chemical peptide synthesis from fermentation- or hydrolysate-derived amino acids. Recombinant or enzymatic production, where used, also yields only amino-acid mass, so the value is unchanged.

In plain English

A 40-amino-acid peptide added to skin-care products as a skin-conditioning ingredient. It is assembled in a laboratory by joining amino acids, the building blocks of proteins, which are produced by fermentation or from hydrolysed plant and animal protein.

CosIng definition: Oligopeptide-27 is a synthetic peptide containing 40 amino acids consisting of alanine, arginine, asparagine, aspartic acid, glutamic acid, glutamine, glycine, isoleucine, lysine, methionine, proline, serine, threonine, tyrosine, and valine; Alanine, synthetic 40-unit peptide with arginine, asparagine, aspartic acid, glutamic acid, glutamine, glycine, isoleucine, lysine, methionine, proline, serine, threonine, tyrosine, and valine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-27. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-27. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-27