Database/Skin Conditioning/Oligopeptide-21
100% natural origin · ISO 16128

Is Oligopeptide-21 natural?

Yes. Built solely from standard amino acids (fermentation-derived); peptide-bond-forming reagents leave no mass in the final peptide.

INCI nameOligopeptide-21
FunctionSkin Conditioning
FeedstockChemically synthesised from the standard amino acids arginine,…

How we scored it

Dodecapeptide of arginine, aspartic acid, glutamic acid, leucine, phenylalanine, serine; amino acids are natural and coupling reagents leave no mass, so 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Chemically synthesised from the standard amino acids arginine, aspartic acid, glutamic acid, leucine, phenylalanine and serine, sourced from fermentation or protein hydrolysis. No petrochemical route exists.

In plain English

A lab-made peptide built from natural amino acids, used to condition skin. The building blocks come from fermentation, not petroleum.

CosIng definition: Oligopeptide-21 is a synthetic peptide containing 12 amino acids consisting of arginine, aspartic acid, glutamic acid, leucine, phenylalanine and serine; Arginine, synthetic dodecapeptide with aspartic acid, glutamic acid, leucine, phenylalanine and serine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-21. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-21. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-21