Database/Skin Conditioning/Oligopeptide-20
100% natural origin · ISO 16128

Is Oligopeptide-20 natural?

Yes. A plain synthetic peptide with no fatty or acetyl modification; residues are fermentation-derived amino acids.

INCI nameOligopeptide-20
CAS948884-07-9
FormulaC65H109N19O16S2 · 1476.8 Da
FunctionSkin Conditioning
FeedstockSynthesised from fermentation-derived amino acids by peptide synthesis.…

How we scored it

12-residue peptide (Ala, Arg, Cys, Glu, Leu, Lys, Met, Pro, Tyr) with no acyl cap described; amide-linked amino acids are natural. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesised from fermentation-derived amino acids by peptide synthesis. No extraction route exists at commercial scale.

In plain English

A lab-assembled chain of 12 amino acids used for skin conditioning. The building blocks come from fermentation, even though the finished peptide is made synthetically.

CosIng definition: Oligopeptide-20 is a synthetic 12 amino acid peptide consisting of alanine, arginine, cysteine, glutamic acid, leucine, lysine, methionine, proline and tyrosine

Structure

2D structure of Oligopeptide-20

(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-sulfanylpropanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid

PubChem CID 169450586 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Oligopeptide-20. PubChem CID 169450586. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OLIGOPEPTIDE-20. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OLIGOPEPTIDE-20. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-20