Database/Skin Conditioning/Oligopeptide-18
100% natural origin · ISO 16128

Is Oligopeptide-18 natural?

Yes. Synthesized from standard fermentation-derived amino acids via peptide coupling; backbone entirely amino-acid derived.

INCI nameOligopeptide-18
FunctionSkin Conditioning
FeedstockChemically synthesized from the listed amino acids (fermentation-derived)…

How we scored it

12 natural amino acids (incl. cystine) joined by peptide bonds; synthesis reagents leave no mass — 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Chemically synthesized from the listed amino acids (fermentation-derived) via standard peptide-coupling chemistry. No alternative route is significant.

In plain English

A lab-made short peptide formulated to condition and support the skin, used in moisturizing and anti-aging products.

CosIng definition: Oligopeptide-18 is a synthetic 12 amino acid peptide consisting of alanine, cystine, leucine, lysine, proline, serine and tyrosine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-18. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-18. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-18