Database/Skin Protecting/Oligopeptide-12
100% natural origin · ISO 16128

Is Oligopeptide-12 natural?

Yes. Every residue derives from fermentation- or hydrolysate-sourced amino acids, and condensation water is not counted, so the whole peptide is natural origin.

INCI nameOligopeptide-12
FunctionSkin Protecting
FeedstockAmino acids from fermentation or protein hydrolysate are…

How we scored it

15-residue peptide of proteinogenic amino acids only, all n=1; no acetyl or acyl cap named, so 1.0. Synthesis reagents and protecting groups leave no mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Amino acids from fermentation or protein hydrolysate are assembled by solid-phase or solution peptide synthesis. Recombinant or enzymatic assembly is an alternative and gives the same natural-origin value.

In plain English

A peptide chain of 15 amino acids, made in a laboratory and listed as a skin-protecting ingredient. It is built from common amino acids, which come from fermentation or from hydrolysed plant or animal protein.

CosIng definition: Oligopeptide-12 is a synthetic 15 amino acid peptide consisting of alanine, asparagine, glutamine, glycine, isoleucine, leucine, lysine, proline, threonine and valine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OLIGOPEPTIDE-12. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OLIGOPEPTIDE-12. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLIGOPEPTIDE-12