Database/Antioxidant/Oleuropein
100% natural origin · ISO 16128

Is Oleuropein natural?

Yes. Signature bitter glycoside of olive leaf and fruit, obtained by extraction; no commercial synthetic route exists.

INCI nameOleuropein
CAS32619-42-4
FormulaC25H32O13 · 540.5 Da
FunctionAntioxidant · Hair Conditioning
FeedstockExtracted from olive leaves, Olea europaea, where it…

How we scored it

Natural olive secoiridoid glycoside; extracted intact from olive leaf, all 540.5 Da is plant-derived, so 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Extracted from olive leaves, Olea europaea, where it is the dominant natural phenolic compound. There is no commercially significant synthetic route given the molecule's complexity.

In plain English

A powerful antioxidant compound naturally abundant in olive leaves. It's extracted directly from the leaves, not manufactured.

CosIng definition: Oleuropein is the organic compound that conforms to the formula:

Structure

2D structure of Oleuropein

methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate

PubChem CID 5281544 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Oleuropein. PubChem CID 5281544. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OLEUROPEIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OLEUROPEIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLEUROPEIN