Database/Cleansing Surfactant/Oleoyl Glycine
100% natural origin · ISO 16128

Is Oleoyl Glycine natural?

Yes. Oleic acid, oleochemical, and glycine, a fermentation amino acid, are both natural; the acid-chloride activation step leaves no residue.

INCI nameOleoyl Glycine
CAS2601-90-3
FormulaC20H37NO3 · 339.5 Da
FunctionCleansing Surfactant
FeedstockMade by acylating glycine, a fermentation-derived amino acid,…

How we scored it

Formula checks exactly: oleic acid (282 Da) + glycine (75 Da) - water (18) = 339.5 Da. Acid-chloride activation leaves no residue; both fragments natural = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acylating glycine, a fermentation-derived amino acid, with oleic acid activated as its acid chloride. The chlorine leaves as HCl and is not part of the final molecule.

In plain English

A gentle cleansing ingredient made by combining a vegetable-oil fatty acid with glycine, a simple amino acid. Used in cleansers for mild foaming and skin conditioning.

CosIng definition: Oleoyl Glycine is the acylation product of glycine with oleic acid chloride. It conforms to the formula

Structure

2D structure of Oleoyl Glycine

2-[[(Z)-octadec-9-enoyl]amino]acetic acid

PubChem CID 6436908 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Oleoyl Glycine. PubChem CID 6436908. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3OLEOYL GLYCINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4OLEOYL GLYCINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OLEOYL%20GLYCINE