Database/Skin Protecting/Octapeptide-8
100% natural origin · ISO 16128

Is Octapeptide-8 natural?

Yes. All residues are proteinogenic amino acids from fermentation or protein hydrolysate; coupling agents and protecting groups leave no mass in the product.

INCI nameOctapeptide-8
FunctionSkin Protecting
FeedstockDominant route is chemical peptide synthesis from fermentation-derived…

How we scored it

Sum of residues (Asn, Asp, Ile, Leu, Lys, Val) is 100% natural origin; no acyl or acetyl cap in the INCI name (end groups not stated). 100% / 100% = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route is chemical peptide synthesis from fermentation-derived amino acids, with reagents and protecting groups leaving no mass. Recombinant or enzymatic assembly is a less common alternative with identical atoms.

In plain English

A short chain of eight amino acids made by laboratory synthesis, used in skin-care products as a skin-protecting ingredient. It is built from asparagine, aspartic acid, isoleucine, leucine, lysine and valine, the same amino acids found in natural proteins.

CosIng definition: Octapeptide-8 is the synthetic peptide consisting of asparagine, aspartic acid, isoleucine, leucine, lysine and valine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2OCTAPEPTIDE-8. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3OCTAPEPTIDE-8. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OCTAPEPTIDE-8