How we scored it
8-residue peptide (glutamic acid, glutamine, leucine, lysine, threonine); amino acids natural = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Synthesized from glutamic acid, glutamine, leucine, lysine and threonine, amino acids from fermentation or protein hydrolysis. No petrochemical mass remains in the assembled peptide.
In plain English
A small chain of eight amino acids assembled in a lab from natural amino-acid building blocks. Used in skin care as a conditioning ingredient.
CosIng definition: Octapeptide-2 is a synthetic peptide composed of glutamic acid, glutamine, leucine, lysine, and threonine
Structure
(2S)-5-amino-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxybutanoyl]amino]-5-oxopentanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Octapeptide-2. PubChem CID 16657324. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3OCTAPEPTIDE-2. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4OCTAPEPTIDE-2. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=OCTAPEPTIDE-2