Database/Skin Conditioning/N-Hydroxysuccinimide
100% petroleum · ISO 16128

Is N-Hydroxysuccinimide natural?

No. Fine chemical/coupling-agent building block manufactured from petrochemical maleic anhydride with no natural feedstock route.

INCI nameN-Hydroxysuccinimide
CAS6066-82-6
FormulaC4H5NO3 · 115.09 Da
FunctionSkin Conditioning
FeedstockProduced synthetically from maleic anhydride (a petrochemical, from…

How we scored it

Succinimide ring industrially made from petrochemical maleic anhydride + hydroxylamine; no natural production route relevant to cosmetics → 0.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Produced synthetically from maleic anhydride (a petrochemical, from benzene or butane oxidation) and hydroxylamine. No natural or fermentation route is used industrially.

In plain English

A manufactured chemical building block, normally used to help other ingredients bond together during manufacturing. Listed here as a skin-conditioning ingredient in the finished product.

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Structure

2D structure of N-Hydroxysuccinimide

1-hydroxypyrrolidine-2,5-dione

PubChem CID 80170 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2N-Hydroxysuccinimide. PubChem CID 80170. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3N-HYDROXYSUCCINIMIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4N-HYDROXYSUCCINIMIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=N-HYDROXYSUCCINIMIDE