Database/Skin Conditioning/Myristoyl Pentapeptide-11
100% natural origin · ISO 16128

Is Myristoyl Pentapeptide-11 natural?

Yes. Myristic acid is oleochemical and every amino acid is a fermentation or protein-hydrolysate product; coupling reagents and resins leave no mass in the peptide.

INCI nameMyristoyl Pentapeptide-11
CAS959610-32-3
FormulaC38H72N8O8S · 801.1 Da
FunctionSkin Conditioning
FeedstockAmino acids from fermentation or protein hydrolysis are…

How we scored it

C38H72N8O8S 801.1: myristoyl C14H27O (coconut or palm kernel) plus five amino acid residues; amino acids, fatty acid and any C-terminal amide treated as natural; resin and coupling reagents leave no mass; 801.1 / 801.1 = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Amino acids from fermentation or protein hydrolysis are assembled by solid-phase peptide synthesis and acylated with myristic acid from coconut or palm kernel oil. Some amino acids are synthesised at bulk scale, but the site this site's method scores peptides as natural origin.

In plain English

A small peptide of five amino acids attached to myristic acid, a fatty acid from coconut or palm kernel oil. It is assembled in a laboratory from amino acids and used as a skin-conditioning ingredient.

CosIng definition: Myristoyl Pentapeptide-11 is the product of the reaction of myristic acid and Pentapeptide-11

Structure

2D structure of Myristoyl Pentapeptide-11

(4S)-4-[[2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]hexanoyl]amino]acetyl]amino]-5-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

PubChem CID 168490220 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Myristoyl Pentapeptide-11. PubChem CID 168490220. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3MYRISTOYL PENTAPEPTIDE-11. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4MYRISTOYL PENTAPEPTIDE-11. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=MYRISTOYL%20PENTAPEPTIDE-11