Database/Antimicrobial/Miconazole Nitrate
100% petroleum · ISO 16128

Is Miconazole Nitrate natural?

No. Built from chlorinated benzene derivatives and synthetic imidazole; nitrate counter-ion is industrially synthesized, not a natural mineral.

INCI nameMiconazole Nitrate
CAS22832-87-7
FormulaC18H15Cl4N3O4 · 479.1 Da
FunctionAntimicrobial
FeedstockManufactured by multi-step organic synthesis from chlorobenzene and…

How we scored it

Miconazole cation (dichlorophenyl + imidazole) entirely petrochemical aromatic/heterocyclic synthesis; nitrate is industrial (ammonia oxidation), not a listed natural mineral salt = 0/479 = 0.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by multi-step organic synthesis from chlorobenzene and imidazole precursors, salified with nitric acid. No natural route exists.

In plain English

A synthetic antifungal ingredient used to control microbial growth in a product.

CosIng definition: Miconazole Nitrate is the heterocyclic compound that conforms to the formula:

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Structure

2D structure of Miconazole Nitrate

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole;nitric acid

PubChem CID 68553 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Miconazole Nitrate. PubChem CID 68553. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3MICONAZOLE NITRATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4MICONAZOLE NITRATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=MICONAZOLE%20NITRATE