Database/Humectant/Methylsilanol PCA
Mostly natural · ISO 16128

Is Methylsilanol PCA natural?

Mostly. PCA fragment derives from fermentation-produced glutamic acid; the methylsilanol fragment is synthetic organosilicon, scored 0.

INCI nameMethylsilanol PCA
CAS105883-41-8
FormulaC6H11NO5Si · 205.24 Da
FunctionHumectant · Skin Conditioning
FeedstockPCA (pyroglutamic acid) is made from fermentation-derived L-glutamic…

How we scored it

PCA (pyroglutamate from L-glutamic acid, ~128 Da, natural) esterified to methylsilanetriol (organosilicon, ~77 Da, scored 0 by convention); 128/205=0.62.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

PCA (pyroglutamic acid) is made from fermentation-derived L-glutamic acid, then esterified with a synthetic methylsilanetriol from organosilicon chemistry.

In plain English

A moisture-binding ingredient combining a natural amino-acid derivative, made from fermented glutamic acid, with a small silicon-based molecule made through industrial chemistry.

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Structure

2D structure of Methylsilanol PCA

[dihydroxy(methyl)silyl] (2S)-5-oxopyrrolidine-2-carboxylate

PubChem CID 72941639 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Methylsilanol PCA. PubChem CID 72941639. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3METHYLSILANOL PCA. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4METHYLSILANOL PCA. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=METHYLSILANOL%20PCA