Database/Skin Conditioning/MEA-Biotinate
100% petroleum · ISO 16128

Is MEA-Biotinate natural?

No. Commercial biotin is made by multi-step chemical synthesis from petrochemical building blocks, and monoethanolamine from ethylene oxide and ammonia, so neither fragment is credited as natural origin.

INCI nameMEA-Biotinate
FunctionSkin Conditioning
FeedstockBiotin is synthesised chemically and neutralised with monoethanolamine…

How we scored it

Biotin C10H16N2O3S 244.3 Da assumed chemical synthesis (0); monoethanolamine C2H7NO 61.1 Da from ethylene oxide and ammonia (0); 0 / 305.4 = 0.00. Fermentation biotin would give 244.3 / 305.4 = 0.80.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Biotin is synthesised chemically and neutralised with monoethanolamine (ethylene oxide plus ammonia). Fermentation-derived biotin exists at small scale and would raise the value to about 0.80.

In plain English

The monoethanolamine salt of biotin (vitamin B7), used as a skin-conditioning ingredient in cosmetics. The vitamin is mainly made by chemical synthesis and combined with monoethanolamine, an amine made from ethylene oxide and ammonia.

CosIng definition: MEA-Biotinate is the monoethanolamine salt of Biotin that conforms to the formula:

Natural alternatives with the same function

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2MEA-BIOTINATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3MEA-BIOTINATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=MEA-BIOTINATE