How we scored it
Triterpenoid glycoside extracted intact from Centella asiatica, no synthetic step → total/total = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Extracted and purified from the Centella asiatica (gotu kola) plant, where it occurs naturally. No chemical synthesis is involved in its production.
In plain English
A soothing, antioxidant active compound used in skincare for sensitive or irritated skin. It is a natural compound extracted and purified from the Centella asiatica (gotu kola) plant.
Structure
[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Madecassoside. PubChem CID 24825675. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3MADECASSOSIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4MADECASSOSIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=MADECASSOSIDE