Database/Skin Conditioning/Madecassic Acid
100% natural origin · ISO 16128

Is Madecassic Acid natural?

Yes. A single triterpenoid acid isolated from the Centella asiatica plant; no commercial petrochemical synthesis route exists.

INCI nameMadecassic Acid
CAS18449-41-7
FormulaC30H48O6 · 504.7 Da
FunctionSkin Conditioning
FeedstockPurified from extracts of the Asiatic pennywort plant…

How we scored it

Pentacyclic triterpene acid extracted/purified from Centella asiatica; natural plant fragment = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Purified from extracts of the Asiatic pennywort plant (Centella asiatica) by extraction and purification. Not manufactured from petrochemical starting materials.

In plain English

A skin-conditioning compound purified from the Centella asiatica (gotu kola) plant, related to asiaticoside. It is isolated directly from the plant rather than synthesised.

Structure

2D structure of Madecassic Acid

(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

PubChem CID 73412 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Madecassic Acid. PubChem CID 73412. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3MADECASSIC ACID. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4MADECASSIC ACID. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=MADECASSIC%20ACID