Database/Antistatic/Lysine PCA
100% natural origin · ISO 16128

Is Lysine PCA natural?

Yes. Both the amino acid and the PCA counter-ion trace to fermentation-derived amino acids.

INCI nameLysine PCA
CAS97635-57-9
FormulaC11H21N3O5 · 275.30 Da
FunctionAntistatic · Humectant
FeedstockL-lysine and PCA (pyroglutamic acid, made by cyclising…

How we scored it

Lysine (fermentation amino acid) + PCA, pyroglutamic acid from natural glutamic-acid cyclisation, both natural -> whole salt 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

L-lysine and PCA (pyroglutamic acid, made by cyclising fermentation-derived glutamic acid) are both produced by fermenting plant sugars, then combined as a salt. No petrochemical fragment is present.

In plain English

A moisture-binding salt made by combining the amino acid lysine with PCA, a natural part of skin's own moisturising system. Both components come from fermented plant sugars.

Structure

2D structure of Lysine PCA

(2S)-2,6-diaminohexanoic acid;(2S)-5-oxopyrrolidine-2-carboxylic acid

PubChem CID 23534249 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Lysine PCA. PubChem CID 23534249. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3LYSINE PCA. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4LYSINE PCA. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=LYSINE%20PCA