Database/Humectant/Licochalcone A
100% natural origin · ISO 16128

Is Licochalcone A natural?

Yes. Plant-derived chalcone isolated from licorice root; total synthesis not commercially significant.

INCI nameLicochalcone A
CAS58749-22-7
FormulaC21H22O4 · 338.4 Da
FunctionHumectant · Skin Protecting
FeedstockIsolated by extraction from the root of Chinese…

How we scored it

Chalcone extracted from licorice root (Glycyrrhiza inflata); commercial source is extraction, not synthesis = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Isolated by extraction from the root of Chinese licorice (Glycyrrhiza inflata). Marketed as a standardised licorice root extract component.

In plain English

A natural compound extracted from licorice root, valued in skincare for its skin-protecting antioxidant properties. Comes directly from the licorice plant.

CosIng definition: Licochalcone A is the organic compound that conforms to the formula.

Structure

2D structure of Licochalcone A

(E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

PubChem CID 5318998 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Licochalcone A. PubChem CID 5318998. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3LICOCHALCONE A. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4LICOCHALCONE A. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=LICOCHALCONE%20A