Database/Keratinase
100% natural origin · ISO 16128

Is Keratinase natural?

Yes. Keratinase is a protein made only of amino acids, produced by microbial fermentation, so under the mass-balance method it counts as fully natural origin.

INCI nameKeratinase
CAS9025-41-6
FeedstockProduced commercially by fermenting keratinase-secreting bacteria, commonly Bacillus…

How we scored it

Protein enzyme built entirely from amino acids, produced by microbial fermentation; no synthetic modification. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Produced commercially by fermenting keratinase-secreting bacteria, commonly Bacillus species, in culture. There is no petrochemical route to this protein enzyme.

In plain English

Keratinase is an enzyme that breaks down keratin protein. It's typically produced by fermenting bacteria and used in hair- and skin-conditioning formulas.

CosIng definition: Keratinase is a proteolytic enzyme that catalyzes the hydrolysis of keratin

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2KERATINASE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3KERATINASE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=KERATINASE