Database/Humectant/Isosorbide
100% natural origin · ISO 16128

Is Isosorbide natural?

Yes. Formed by acid-catalysed double dehydration of natural, glucose-derived sorbitol; only condensation water leaves the molecule.

INCI nameIsosorbide
CAS652-67-5
FormulaC6H10O4 · 146.14 Da
FunctionHumectant · Skin Conditioning
FeedstockManufactured by dehydrating sorbitol, itself made from corn-…

How we scored it

Double dehydration of sorbitol (from glucose); only water is lost, no external atoms added. 100% natural carbon skeleton.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by dehydrating sorbitol, itself made from corn- or wheat-derived glucose. No petrochemical route is used commercially.

In plain English

A humectant and skin conditioner made by removing water from corn-derived sorbitol. It helps products retain moisture and is fully plant-sourced.

CosIng definition: Isosorbide is the organic compound that conforms to the formula.

Structure

2D structure of Isosorbide

(3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol

PubChem CID 12597 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Isosorbide. PubChem CID 12597. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ISOSORBIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ISOSORBIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ISOSORBIDE