Database/Skin Conditioning/Inosine
100% natural origin · ISO 16128

Is Inosine natural?

Yes. Produced like other nucleosides by microbial fermentation of sugar feedstocks; no petrochemical fragments present.

INCI nameInosine
CAS58-63-9
FormulaC10H12N4O5 · 268.23 Da
FunctionSkin Conditioning · Skin Protecting
FeedstockInosine is manufactured by fermentation of glucose using…

How we scored it

Nucleoside C10H12N4O5: ribose + hypoxanthine, both fermentation-derived, no petrochemical fragment. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Inosine is manufactured by fermentation of glucose using purine-producing microorganisms, the standard commercial route for cosmetic-grade nucleosides.

In plain English

Inosine is a nucleoside that conditions and helps protect skin. It's produced by fermenting plant sugars with microorganisms, the same way several vitamin-like skincare ingredients are made.

Structure

2D structure of Inosine

9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

PubChem CID 135398641 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Inosine. PubChem CID 135398641. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3INOSINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4INOSINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=INOSINE