Database/Hair Dyeing/Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl
Mostly petroleum · ISO 16128

Is Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl natural?

Mostly not. The phenylenediamine core and its hydroxyethyl/hydroxypropyl groups are petrochemical; only the chloride counter-ions are mineral-origin.

INCI nameHydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl
CAS128729-28-2
FormulaC19H32Cl4N4O3 · 506.3 Da
FunctionHair Dyeing
FeedstockSynthesised from petrochemical p-phenylenediamine reacted with ethylene oxide…

How we scored it

Free base C19H28N4O3 (360Da) petrochemical (aniline + ethylene/propylene oxide); 4 HCl (146Da) natural mineral chloride -> 146/506 = 0.29
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesised from petrochemical p-phenylenediamine reacted with ethylene oxide and propylene oxide, then isolated as the tetrahydrochloride salt. No natural route exists for the organic core.

In plain English

A synthetic hair-dye ingredient built from petroleum-derived phenylenediamine and reactive petrochemical oxides, used to develop deep colour shades in permanent hair dye.

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Structure

2D structure of Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl

1,3-bis[4-amino-N-(2-hydroxyethyl)anilino]propan-2-ol;tetrahydrochloride

PubChem CID 21932462 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl. PubChem CID 21932462. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HYDROXYPROPYL BIS(N-HYDROXYETHYL-P-PHENYLENEDIAMINE) HCL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HYDROXYPROPYL BIS(N-HYDROXYETHYL-P-PHENYLENEDIAMINE) HCL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HYDROXYPROPYL%20BIS%28N-HYDROXYETHYL-P-PHENYLENEDIAMINE%29%20HCL