Database/Antistatic/Hydroxyproline
100% natural origin · ISO 16128

Is Hydroxyproline natural?

Yes. Commercially obtained by hydrolysing natural collagen/gelatin or by fermentation, both natural-origin processes.

INCI nameHydroxyproline
CAS51-35-4
FormulaC5H9NO3 · 131.13 Da
FunctionAntistatic · Hair Conditioning
FeedstockTypically produced by acid hydrolysis of animal collagen…

How we scored it

Modified amino acid obtained from collagen hydrolysis or fermentation; both routes natural origin = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Typically produced by acid hydrolysis of animal collagen or gelatin (e.g. bovine or fish-derived), or increasingly by microbial fermentation. No petrochemical synthetic route is used commercially.

In plain English

An amino acid found in collagen, used to condition hair and skin and reduce static. Typically obtained by breaking down collagen or gelatin, or by fermentation.

Structure

2D structure of Hydroxyproline

(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid

PubChem CID 5810 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Hydroxyproline. PubChem CID 5810. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HYDROXYPROLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HYDROXYPROLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HYDROXYPROLINE