Database/Antioxidant/Hydroxyacetophenone
100% petroleum · ISO 16128

Is Hydroxyacetophenone natural?

No. Phenol (from benzene and propylene) and an acetyl group from acetic acid or anhydride are both petrochemical, so no atoms trace to natural feedstock.

INCI nameHydroxyacetophenone
CAS99-93-4
FormulaC8H8O2 · 136.15 Da
FunctionAntioxidant
FeedstockThe dominant route is Fries rearrangement or Friedel-Crafts…

How we scored it

C8H8O2 136 Da: the phenol-derived ring and the acetyl group (acetic acid or anhydride) are both petrochemical; no natural fragment. 0/136 = 0.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

The dominant route is Fries rearrangement or Friedel-Crafts acylation of phenol with acetic acid, acetic anhydride or acetyl chloride, all petrochemical. The compound also occurs in trace amounts in some plants, but no commercially significant natural-extraction or bio-based route supplies cosmetic grades.

In plain English

A small aromatic compound that acts as an antioxidant and helps stabilise and preserve cosmetic formulas, often alongside other preservatives. It occurs in traces in some plants but is made industrially from phenol and an acetyl source.

CosIng definition: Hydroxyacetophenone is the organic compound

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Structure

2D structure of Hydroxyacetophenone

1-(4-hydroxyphenyl)ethanone

PubChem CID 7469 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Hydroxyacetophenone. PubChem CID 7469. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HYDROXYACETOPHENONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HYDROXYACETOPHENONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HYDROXYACETOPHENONE