Database/Antioxidant/Honokiol
100% natural origin · ISO 16128

Is Honokiol natural?

Yes. Commercial supply is purification from Magnolia bark; no significant petrochemical synthesis route is used for cosmetic-grade material.

INCI nameHonokiol
CAS35354-74-6
FormulaC18H18O2 · 266.3 Da
FunctionAntioxidant · Bleaching
FeedstockIsolated by extraction and purification from Magnolia officinalis…

How we scored it

Natural biphenyl neolignan isolated whole from Magnolia bark extract; molecule pre-exists in the plant, no fragments to split.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Isolated by extraction and purification from Magnolia officinalis or M. obovata bark. Laboratory total synthesis exists but is not the commercial cosmetic-ingredient route.

In plain English

An antioxidant compound isolated from magnolia tree bark, used in skincare to help protect skin and even out tone.

Structure

2D structure of Honokiol

2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol

PubChem CID 72303 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Honokiol. PubChem CID 72303. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HONOKIOL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HONOKIOL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HONOKIOL