Database/Hair Conditioning/Histidine HCl
100% natural origin · ISO 16128

Is Histidine HCl natural?

Yes. Amino acid salt of histidine with chloride, a natural mineral counter-ion; both fragments natural origin.

INCI nameHistidine HCl
CAS645-35-2
FormulaC6H10ClN3O2 · 191.61 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockHistidine is produced by fermentation or protein hydrolysis…

How we scored it

Histidine (fermentation amino acid) + HCl mineral counter-ion, both natural; 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Histidine is produced by fermentation or protein hydrolysis and sold as its hydrochloride salt for stability. The chloride counter-ion is mineral in origin.

In plain English

The hydrochloride salt form of histidine, an amino acid, used to condition hair and skin. Made by fermentation, then combined with a mineral salt for stability.

Structure

2D structure of Histidine HCl

(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrochloride

PubChem CID 66091 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Histidine HCl. PubChem CID 66091. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HISTIDINE HCL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HISTIDINE HCL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HISTIDINE%20HCL