How we scored it
Hexapeptide-5 is a synthetic peptide of valine, tyrosine, glutamic acid, proline and isoleucine, all standard amino acids from fermentation; peptide bonds lose only water → 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Solid-phase peptide synthesis from standard amino acids.
In plain English
A lab-assembled chain of amino acids with a small synthetic cap at one end, used to condition skin. Almost all of its structure comes from the same natural building blocks found in proteins.
CosIng definition: Hexapeptide-5 is a synthetic peptide containing Valine, Tyrosine, Glutamic Acid, Proline and Isoleucine residues
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2HEXAPEPTIDE-5. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3HEXAPEPTIDE-5. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HEXAPEPTIDE-5