How we scored it
Peptide built from amino acids (Ala, His, Lys, Phe, Trp residues); synthesis reagents/coupling agents leave no mass. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Assembled from naturally-sourced amino acids (alanine, histidine, lysine, phenylalanine, tryptophan) via solid-phase peptide synthesis. The synthesis reagents and coupling agents do not remain in the final product.
In plain English
A lab-assembled chain of natural amino acids used for skin conditioning. It is built from the same building blocks found in proteins, linked together in a specific order.
CosIng definition: Hexapeptide-2 is a synthetic peptide containing Alanine, histidine, lysine, phenylalanine and tryptophane hexapeptide
Structure
(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Hexapeptide-2. PubChem CID 9919153. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3HEXAPEPTIDE-2. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4HEXAPEPTIDE-2. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HEXAPEPTIDE-2