How we scored it
Peptide of Ala/Phe/Pro/Val residues, no non-amino-acid cap in description; amino acids are natural-origin = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Synthesized by chemically linking fermentation-derived amino acids into a defined six-residue chain. No petrochemical fragment remains in the final peptide.
In plain English
A lab-assembled chain of four types of amino acids used to condition skin. The amino acid building blocks typically come from fermentation.
CosIng definition: Hexapeptide-11 is a synthetic peptide containing Alanine, Phenylalanine, Proline and Valine residues
Structure
(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Hexapeptide-11. PubChem CID 24998056. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3HEXAPEPTIDE-11. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4HEXAPEPTIDE-11. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HEXAPEPTIDE-11