How we scored it
6-residue peptide (alanine, isoleucine, lysine, serine, valine); amino acids natural = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Synthesized from alanine, isoleucine, lysine, serine and valine, amino acids from fermentation or protein hydrolysis. No petrochemical mass remains in the assembled peptide.
In plain English
A small chain of six amino acids assembled in a lab from natural amino-acid building blocks. Used in cosmetics to help draw and retain moisture in the skin.
CosIng definition: Hexapeptide-10 is a synthetic peptide containing Alanine, Isoleucine, Lysine, Serine and Valine residues
Structure
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Hexapeptide-10. PubChem CID 10145673. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3HEXAPEPTIDE-10. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4HEXAPEPTIDE-10. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HEXAPEPTIDE-10