Database/Emollient/Hesperidin
100% natural origin · ISO 16128

Is Hesperidin natural?

Yes. Extracted directly from citrus peel; the whole glycoside molecule is plant-derived.

INCI nameHesperidin
CAS520-26-3
FormulaC28H34O15 · 610.6 Da
FunctionEmollient
FeedstockExtracted and purified from citrus peel (commonly orange…

How we scored it

Natural citrus flavanone glycoside, extracted intact from plant material; 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Extracted and purified from citrus peel (commonly orange or lemon) processing byproducts. No commercial synthetic route exists.

In plain English

A plant compound extracted from citrus peel, valued for its antioxidant and skin-soothing properties. Used in skincare to support the look of healthy skin.

Structure

2D structure of Hesperidin

(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one

PubChem CID 10621 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Hesperidin. PubChem CID 10621. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HESPERIDIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HESPERIDIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HESPERIDIN