Database/Antioxidant/Hesperetin
100% natural origin · ISO 16128

Is Hesperetin natural?

Yes. Produced by hydrolyzing hesperidin extracted from citrus peel; hydrolysis removes only a sugar unit, adding no petrochemical mass.

INCI nameHesperetin
CAS520-33-2
FormulaC16H14O6 · 302.28 Da
FunctionAntioxidant · Skin Conditioning
FeedstockMade by acid or enzymatic hydrolysis of hesperidin,…

How we scored it

Natural citrus flavonoid aglycone; commercial route is hydrolysis of natural hesperidin from citrus peel. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by acid or enzymatic hydrolysis of hesperidin, a flavonoid glycoside extracted from citrus peel such as orange or lemon. No significant petrochemical synthetic route is used commercially.

In plain English

An antioxidant flavonoid derived from citrus peel, used in skincare to help protect skin from environmental stress and even out tone.

Structure

2D structure of Hesperetin

(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one

PubChem CID 72281 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Hesperetin. PubChem CID 72281. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3HESPERETIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4HESPERETIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=HESPERETIN